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. 2020 Mar 10;72(3):730–743. doi: 10.1007/s43440-020-00080-8

Table 2.

The distribution of FKBP5 rs1360780, BDNF rs6265, and NRN1 rs1475157 alleles in AD patients (n = 176) and the controls (n = 127), divided by low, medium, and high GSES outcomes

GSES Low Medium High p
n % n % n %
BDNF rs6265
 AD patients C 39 22.3 47 26.9 89 50.9 0.2271
T 17 28.8 14 23.7 28 47.5 0.3731
 Controls C 10 8.1 114 91.9 > 0.9991
T 2 6.1 31 93.9 > 0.9991
 AD patients vs C 0.2601
 Controls T 0.7081 0.4352
FKBP5 rs1360780
 AD patients C 39 23.5 43 25.9 84 50.6 0.5271
T 16 21.9 21 28.8 36 49.3 0.8722
 Controls C 10 8.5 107 91.5 > 0.9991
T 3 4.6 62 95.4 0.1991
 AD patients vs C > 0.9991 0.4232
 Controls T 0.4941 0.074
NRN1 rs1475157
 AD patients A 38 22.1 46 26.7 88 51.2 0.3451
G 10 21.3 14 29.8 23 48.9 0.8522
 Controls A 10 7.9 117 92.1 > 0.9991
G 2 5.6 34 94.4 0.7241
 AD patients vs A > 0.9991 0.6351
 Controls G 0.708 0.6092

p level of statistical significance with Bonferroni correction

GSES generalized self-efficacy scale, AD alcohol-dependent

1Fisher’s exact test

2Chi square test