Table 1:
Comparisons of characteristics and outcomes between patients whose charts were reviewed compared with sampled patients whose charts were not reviewed.
| Variable | Proven Infected (n=758) | Probably Infected (n=554) | Possibly Infected (n=124) | Unlikely Infected (n=381) | Not Infected (n=1057) | Not Chart Reviewed (n=2341) | p-value |
|---|---|---|---|---|---|---|---|
| Age, years (median (IQR)) | 65 (51–79) | 64 (49–79) | 65 (53–78) | 64 (49–75) | 61 (47–71) | 60 (42–73) | <0.01 |
| Female (%) | 54.1 | 51.3 | 57.3 | 53.0 | 53.9 | 59.5 | <0.01 |
| Black (%) | 29.6 | 27.4 | 29.0 | 38.3 | 22.0 | 27.1 | <0.01 |
| Admission source (%) ED Ward ICU Other* |
57.3 28.2 9.2 5.3 |
62.1 24.5 6.0 7.4 |
58.1 33.1 6.5 2.4 |
61.2 26.0 6.3 6.6 |
21.2 30.5 6.6 41.7 |
43.6 30.0 2.9 23.5 |
<0.01 |
| Co-morbidities (Elixhauser, %) CPD Diabetes Renal Failure Liver Disease Solid Tumor Liquid Tumor Metastatic Cancer |
9.4 26.0 19.8 8.2 12.1 9.1 6.6 |
11.7 19.7 11.7 4.7 10.5 2.9 5.4 |
25.8 19.4 13.7 5.6 19.4 6.5 13.7 |
12.9 20.7 24.1 8.1 15.7 2.1 10.0 |
6.7 16.6 9.6 5.9 12.6 3.5 5.8 |
7.1 17.8 8.2 2.9 9.5 0.9 3.9 |
<0.01 |
| Had OR visit during hospitalization (%) | 24.8 | 16.6 | 16.1 | 18.1 | 64.1 | 24.6 | <0.01 |
| Highest temperature, C° (median (IQR)) | 37.7 (37.2–38.6) | 37.6 (37.1–38.3) | 37.4 (37–37.9) | 37.4 (37.1–38) | 37.3 (37.1–37.7) | 37.1 (36.8–37.3) | <0.01 |
| Highest bands, % (median (IQR)) | 0 (0–3) | 0 (0–0) | 0 (0–2) | 0 (0–0) | 0 (0–0) | 0 (0–0) | <0.01 |
| Highest WBC, 103/μL (median (IQR)) | 13.8 (9.6–21.3) | 12.5 (8.7–17.5) | 11.8 (8.4–17.6) | 12 (8.1–16.7) | 10.9 (8.4–14.3) | 9.1 (6.8–11.9) | <0.01 |
| Number of SIRS criteria met during hospitalization (median (IQR)) | 2 (1–2) | 2 (1–2) | 2 (1–2) | 2 (1–2) | 1 (1–2) | 1 (1–2) | <0.01 |
| Highest SOFA score (median (IQR)) | 3 (1–6) | 2 (1–4) | 2 (1–4) | 3 (1–5) | 1 (1–3) | 1 (0–2) | <0.01 |
| Length of stay, days (median (IQR)) | 5.8 (3.1–11) | 4 (2.4–6.8) | 4 (1.9–8.6) | 4.3 (2.6–7.5) | 3.2 (2–5.7) | 1.9 (1–3.2) | <0.01 |
| In-hospital mortality (%) | 6.6 | 4.7 | 7.3 | 2.4 | 0.8 | 0.8 | <0.01 |
*
OR, n/a, Interventional/Other, or Hospice
Abbreviations: ED = emergency department; ICU = intensive care unit; CPD = chronic pulmonary disease; OR = operating room; SIRS = systemic inflammatory response syndrome; SOFA = sequential organ failure assessment, WBC = white blood cell