Table 3.

Cox proportional hazards survival analysis of patients in the CgA cohort.

	HR	Univariate 95.0% CI		P	HR	Multivariable 95.0% CI		P
		Lower	Upper			Lower	Upper
Age at Diagnosis	1.09	1.06	1.11	<0.001	1.06	1.03	1.09	<0.001
Sex
Male	Ref
Female	0.83	0.50	1.37	0.457
Race
White	Ref
Non-white	1.70	0.88	3.27	0.112
Charlson-Deyo Score
0	Ref				Ref
1	1.47	0.79	2.76	0.227	1.45	0.68	3.07	0.335
≥2	4.35	2.11	8.99	<0.001	3.93	1.71	9.01	0.001
Number of Prior Malignancies
0	Ref				Ref
1	2.51	1.14	5.52	0.022	1.11	0.41	3.00	0.844
Primary Site
Jejunum	Ref				Ref
Ileum	0.44	0.17	1.13	0.089	0.55	0.15	1.98	0.362
Overlapping Lesions of SB	4.62	1.10	19.48	0.037	3.38	0.61	18.75	0.163
SB NOS	0.79	0.29	2.15	0.638	0.55	0.14	2.06	0.373
Surgical Procedure
Simple / Partial Resection	Ref
Total Resection	0.93	0.52	1.67	0.803
Debulking Surgery	3.33	0.46	24.31	0.236
Radical Resection	1.27	0.54	3.00	0.590
Tumor Size
≤1cm	Ref				Ref
>1cm	3.53	1.28	9.74	0.015	1.41	0.39	5.08	0.596
Differentiation
Well Differentiated	Ref				Ref
Moderately Differentiated	1.18	0.59	2.39	0.640	1.69	0.82	3.48	0.157
Poorly Differentiated	17.68	7.81	40.02	<0.001	11.22	4.16	30.24	<0.001
Preoperative Serum CgA
<139ng/mL	Ref				Ref
≥139ng/mL	3.09	1.87	5.12	<0.001	2.19	1.22	3.92	0.009
Mitotic Count
<2 / 10HPFs	Ref
2–20 / 10HPFs	1.42	0.62	3.25	0.409
>20 / 10HPFS	0.00	0.00	n/a	0.980
pT Stage
T1	Ref				Ref
T2	3.54	0.45	27.68	0.228	1.81	0.18	18.60	0.617
T3	7.60	1.04	55.47	0.046	2.91	0.27	30.96	0.376
T4	8.64	1.14	65.45	0.037	3.09	0.28	34.15	0.358
pN Stage
N0	Ref
N1	1.41	0.51	3.89	0.509
N2	0.82	0.15	4.45	0.814