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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Arch Dis Child Fetal Neonatal Ed. 2021 Jan 21;106(4):446–455. doi: 10.1136/archdischild-2020-319705

Figure 4. The vicious cycle of pulmonary hypertension, systemic hypotension and cardiac dysfunction in PPHN.

Figure 4.

Selective pulmonary vasodilators to treat pulmonary hypertension, selective systemic vasoconstrictors to treat systemic hypotension and/or reducing afterload / optimizing preload are important strategies to interrupt this vicious cycle. Modified from an unpublished e-review by Dany Weisz, Patrick McNamara and Amish Jain. Copyright Satyan Lakshminrusimha.