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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Arch Dis Child Fetal Neonatal Ed. 2021 Jan 21;106(4):446–455. doi: 10.1136/archdischild-2020-319705
Indication Refractory pulmonary hypertension and systemic hypotension, however no literature in earlier use
Dose 0.1 to 2 milliunits (mU)/kg/min
Precautions Hyponatremia, systemic vasoconstriction may affect mesenteric perfusion and tolerance/safety of feeding, and may be deleterious in the setting of LV dysfunction.
Contraindications Hyponatremia
Class of Recommendation Class IIb – Usefulness/efficacy is less well established by evidence/opinion. May be considered
Level of Evidence C – Consensus of opinion of the experts and/or small studies, retrospective studies, registries