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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Arch Dis Child Fetal Neonatal Ed. 2021 Jan 21;106(4):446–455. doi: 10.1136/archdischild-2020-319705
Indication Decreased cardiac function, hypotension, hypoxemia
Dose 2 to 20 mcg/kg/min (doses > 10-15 mcg/kg/min likely to have pulmonary vasoconstriction)
Precautions May increase pulmonary pressure further adding to RV afterload;
Watch for extravasation – (extravasation will need therapy with Phentolamine)
Contraindications Supra-physiologic systemic pressures
Class of Recommendation Class IIb – Usefulness/efficacy is less well established by evidence/opinion. May be considered
Level of Evidence C – Consensus of opinion of the experts and/or small studies, retrospective studies, registries