Indication | Hypotension without decreased cardiac function, hypoxemia |
Dose | 0.05 to 0.5 mcg/kg/min – occasionally may need up to 1 mcg/kg/min in PPHN with severe hypotension24 |
Precautions | Increased systemic vasoconstriction may decrease mesenteric perfusion and tolerance/safety of feeding Watch for extravasation – (extravasation will need therapy with Phentolamine) |
Contraindications | Significant cardiac dysfunction unless using with an inotropic agent as well |
Class of Recommendation | Class IIa – Weight of evidence/opinion is in favor of usefulness/efficacy. Should be considered |
Level of Evidence | C – Consensus of opinion of the experts and/or small studies, retrospective studies, registries |