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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Arch Dis Child Fetal Neonatal Ed. 2021 Jan 21;106(4):446–455. doi: 10.1136/archdischild-2020-319705
Indication Decreased cardiac function with risk of arrhythmia
Dose 6 to 12 mcg/kg loading dose over 30 min followed by 0.1 mcg/kg/min for 6 h and then increase to 0.2 mcg/kg/min if tolerated
Precautions Reduce milrinone dose if used concomitantly
Contraindications Asphyxia due to potential altered affects in the pulmonary vasculature following asphyxia
Class of Recommendation Class IIb – Usefulness/efficacy is less well established by evidence/opinion. May be considered
Level of Evidence C – Consensus of opinion of the experts and/or small studies, retrospective studies, registries