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. 2021 Jun 21;11:12970. doi: 10.1038/s41598-021-92346-1

Table 5.

Univariate analysis on the association between clinical and demographic factors and Functional and Symptoms scores on the KORQ Questionnaire.

Variable Functional score Symptoms score
mean ± sd p value mean ± sd p value
Sex
Female 43.22 ± 20.14 0.01 59.75 ± 19.74 0.07
Male 34.48 ± 18.98 52.78 ± 19.01
Age
 ≤ 27 36.60 ± 17.54 0.31 53.09 ± 18.15 0.12
 > 27 42.56 ± 22.44 60.93 ± 20.69
Allergic conjunctivitis
Yes 39.33 ± 20.21 0.94 57.54 ± 18.79 0.58
No 39.19 ± 19.91 54.73 ± 21.41
Visual acuity (better eye, in LOGMAR)
 ≥ 0.3 48.63 ± 19.10  < 0.01 63.94 ± 16.72  < 0.01
 < 0.3 29.56 ± 16.01 48.99 ± 19.68
Corneal curvature steep K (better eye)
 < 52 35.80 ± 16.24 0.24 52.36 ± 19.03 0.16
 ≥ 52 41.08 ± 21.60 58.81 ± 19.71
Pachymetry (better eye)
 > 450 39.24 ± 18.21 0.81 56.45 ± 18.58 0.74
 ≤ 450 39.38 ± 23.27 56.91 ± 21.72
Stage better eye
1 34.92 ± 17.59 0.63 53.15 ± 17.64 0.32
2 40.43 ± 18.77 54.45 ± 18.94
3 39.62 ± 22.42 60.51 ± 20.83
Treatment
No treatment / spectacles 40.73 ± 19.58 0.36 55.56 ± 18.39 0.91
RGP/ICRS/CXL/PKP 37.96 ± 20.50 57.59 ± 20.83
Treatment
No surgical treatments 40.37 ± 20.05 0.44 56.18 ± 19.68 0.88
Surgical treatments 37.44 ± 20.08 57.35 ± 19.79
RGP contact lens
Yes 36.60 ± 21.36 0.45 57.40 ± 22.79 0.79
No 40.23 ± 19.58 56.34 ± 18.55
Crosslinking
Yes 33.22 ± 17.20 0.07 54.91 ± 18.02 0.59
No 41.42 ± 20.59 57.22 ± 20.24
Intraestromal corneal ring
Yes 51.32 ± 15.90 0.18 64.68 ± 21.06 0.20
No 38.38 ± 19.32 56.01 ± 19.50
Penetrating keratoplasty
Yes 43.84 ± 15.55 0.31 62.63 ± 20.43 0.39
No 38.89 ± 20.37 56.09 ± 19.58
RGP contact lens 39.23 ± 22.17 0.39 58.16 ± 23.95
ICRS 49.00 ± 32.10 62.42 ± 25.31 0.71
CXL 32.90 ± 17.71 54.54 ± 18.73
Corneal Transplant 43.84 ± 15.55 62.63 ± 20.43
Hydrops
Yes 40.15 ± 17.50 0.71 61.15 ± 18.46 0.36
No 39.17 ± 20.42 56.00 ± 19.80
General 39.29 ± 20.01 56.62 ± 19.63

CXL corneal collagen cross-linking; RGP rigid permeable gas; ICRS intraestromal corneal rings; PKP penetrating keratoplasty; K keratometry; Data are mean ± standard deviation, unless otherwise indicated.