Figure 3.
A. Men have significantly higher number of somatic mutations across the entire cohort (P<0.001). The difference was also significant among patients with MDS/MPN-U. B. The VAF is higher among men compared to women across the entire cohort (P=0.002). The difference was also significant among MDS/MPN-U patients. C. Competing-risk regression analysis of MDS/MPN-U, CMML and aCML patients showing the incidence of transformation to AML based on the number of somatic mutations (<4 or ≥4) (4 was the median number of somatic mutations). Patients with 4 or more somatic mutations have higher incidence of transformation to AML (P=0.037).