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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Neuropharmacology. 2021 May 7;192:108604. doi: 10.1016/j.neuropharm.2021.108604

Fig. 1:

Fig. 1:

Effects of systemic cocaine on premature responses, omissions and accuracy in the 5CSRTT, and effects of Intra-LHb CB1R antagonism (A) Dose -response relationships for the effects of cocaine on premature responses, response omissions and, % accuracy in the 5CSRTT (n=11, *p<0.05 vs vehicle, Bonferroni’s multiple comparisons test after RM ANOVA). (B) Effects of local LHb infusion of AM251 (0.7 ug) or vehicle on cocaine-altered (5 mg/kg i.p.) behavior in the 5CSRTT (n=9 per group *p<0.05 vs saline, #p<0.05 vs vehicle, Bonferroni’s multiple comparisons test after RM ANOVA). Note that the increase in premature responses caused by 5 mg/kg cocaine was prevented by intra-LHb infusion with AM251.