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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Bone. 2021 Apr 21;149:115971. doi: 10.1016/j.bone.2021.115971

Figure 5: Most Intermediate filaments assemble into a similar secondary structure.

Figure 5:

The basic unit of an intermediate filament is an α-helical monomer. Two monomers coil together to formed a coiled-coil dimer. Two coiled-coil dimers assemble in an anti-parallel fashion to form a tetramer that is apolar and is symmetrical on both ends. Eight tetramers then coil together to form a unit-length filament (ULF). ULFs can then anneal longitudinally to form long intermediate filaments.