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(A) Targeting strategy of Map2k5-targeted allele. Green boxes represent coding regions, gray boxes represent noncoding exon regions, and scissors represent the targeted area of Map2k5 between exons 18 and 22. (B) Primers designed for genotype identification of Map2k5+/– heterozygous and wild-type (WT) mice. (C) PCR results of some Map2k5em41Cd71454 mice.
