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. 2021 Jun 21;11:12973. doi: 10.1038/s41598-021-92332-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Functional classification of high confidence hits. The 75 high confidence hits were classified according to their function using GO terms and literature search. The direction of the bars indicates the sign of the beta score and the color and height indicates the value. Negative and positive beta values indicate genes whose knockout impairs or activates phagocytosis, respectively. Genes in bold are selected for single gene knockout validation.