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. 2021 Jun 21;11:12984. doi: 10.1038/s41598-021-92503-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of the (a) intra- and/or extra-hepatic recurrence rate of hepatocellular carcinoma (HCC) and (b) overall survival rates between the early extrahepatic recurrence (EHR), non-early EHR, and non-EHR groups. The 6-month cumulative recurrence rates among the early EHR, non-early EHR, and non-EHR groups were 77.7%, 39.7%, and 21.9%, respectively. The 1-year, 5-year, and 10-year overall survival rates were 51.6%, 9.7%, and 0% in the early EHR group; 98.4%, 58.7%, and 4.8% in the non-early EHR group; and 96.4%, 63.2%, and 13.2% in the non-EHR group, respectively (p < 0.001).