Table 2.
Comparison of surgical findings in patient groups with and without extrahepatic recurrence.
| Patients without extrahepatic recurrence (n = 304) | Patients with extrahepatic recurrence (n = 94) | p-value | |
|---|---|---|---|
| Margin involvement, n (%) | 9 (3.0) | 6 (6.5) | 0.134 |
| Microvascular invasion, n (%) | 51 (16.9) | 28 (29.8) | 0.006 |
| Serosal invasion, n (%) | 6 (2.1) | 6 (6.5) | 0.034 |
| Bile duct invasion, n (%) | 1 (0.3) | 2 (2.25) | 0.085 |
| Capsule formation, n (%) | 211 (73.3) | 64 (68.8) | 0.405 |
| Multicentricity, n (%) | 34 (11.7) | 9 (9.7) | 0.593 |
| Satellite nodule, n (%) | 38 (13.0) | 29 (31.2) | < 0.001 |
| Underlying liver cirrhosis, n (%) | 201 (66.1) | 61 (64.9) | 0.827 |
| Intrahepatic metastasis, n (%) | 3 (1.0) | 2 (2.1) | 0.830 |
| Necrosis, n (%) | 136 (46.9) | 64 (68.8) | < 0.001 |
| Haemorrhage, n (%) | 139 (47.9) | 53 (57.0) | 0.121 |
| Fatty change, n (%) | 109 (38.0) | 29 (31.9) | 0.291 |
| Cell type, n (%) | 0.213 | ||
|
Clear type Hepatic type Classic type |
53 (17.5) 271 (89.4) 240 (79.2) |
22 (23.4) 89 (94.6) 70 (74.5) |
|
| Major Edmondson Steiner grade, n (%) | 0.336 | ||
|
1/2 3/4 |
14 (4.8)/152 (52.2) 116 (39.9)/9 (3.1) |
4 (4.3)/39 (41.9) 46 (49.5)/4 (4.3) |
|
| Worst Edmondson Steiner grade, n (%) | 0.665 | ||
|
1/2 3/4 |
2 (0.7)/46 (15.8) 178 (61.2)/65 (22.3) |
2 (2.2)/14 (15.1) 55 (59.1)/22 (23.7) |