Table 2.
Design of experiment 23 using 1-butyl-3-methylimidazolium chloride [C6mim][Cl] and 10% water as a co-solvent.
| Test | Number of extractions (X1) | Time of extraction (min; X2) | Cavitation power (W; X3) | Flavonoids (mg RuE. g−1)* | ORAC (μmol TE. g−1) | Predictive ORAC (μmol TE. g−1) | Deviation (%) |
|---|---|---|---|---|---|---|---|
| 1 | 3 (−1) | 5.0 (−1) | 200 (−1) | 398.72 | 4173.39 | 5163.56 | −23.73 |
| 2 | 5 (+1) | 5.0 (−1) | 200 (−1) | 386.55 | 6538.71 | 7398.45 | −13.15 |
| 3 | 3 (−1) | 10.0 (+1) | 200 (−1) | 260.85 | 4678.07 | 5163.56 | −10.38 |
| 4 | 5 (+1) | 10.0 (+1) | 200 (−1) | 392.82 | 7012.41 | 7398.45 | −5.51 |
| 5 | 3 (−1) | 5.0 (−1) | 400 (+1) | 376.65 | 5596.88 | 5163.56 | 7.74 |
| 6 | 5 (+1) | 5.0 (−1 | 400 (+1) | 323.09 | 8034.37 | 7398.45 | 7.92 |
| 7 | 3 (−1) | 10.0 (+1) | 400 (+1) | 355.54 | 4244.95 | 5163.56 | −21.64 |
| 8 | 5 (+1) | 10.0 (+1) | 400 (+1) | 307.04 | 8033.95 | 7398.45 | 7.91 |
| 9 | 2 (−1.68) | 7.5 (0) | 300 (0) | 303.48 | 3921.17 | 3453.96 | 11.91 |
| 10 | 6 (+1.68) | 7.5 (0) | 300 (0) | 384.51 | 6493.30 | 7208.58 | −11.02 |
| 11 | 4 (0) | 3.3 (−1.68) | 300 (0) | 470.96 | 8689.50 | 8011.80 | 7.80 |
| 12 | 4 (0) | 11.7 (+1.68) | 300 (0) | 383.30 | 8019.79 | 8011.80 | 0.10 |
| 13 | 4 (0) | 7.5 (0) | 130 (−1,68) | 447.60 | 5290.34 | 5331.27 | −0.77 |
| 14 | 4 (0) | 7.5 (0) | 470 (+1.68) | 432.01 | 6480.77 | 5331.27 | 17.74 |
| 15 | 4 (0) | 7.5 (0) | 300 (0) | 488.26 | 5794.64 | 5331.27 | 8.00 |
| 16 | 4 (0) | 7.5 (0) | 300 (0) | 435.65 | 6621.68 | 5331.27 | 19.49 |
| 17 | 4 (0) | 7.5 (0) | 300 (0) | 428.47 | 3966.62 | 5331.27 | −34.40 |
The numbers in parentheses correspond to the coded values in the CCDR.
*
The model generated for this response was not predictive.