Table 2.
Comparison of globally VD and ocular parameters between baseline and the end of follow-up period.
| EM (N = 40) | MIM/MOM (N = 194) | HM (N = 75) | p-value | Post-hoc | |
|---|---|---|---|---|---|
| VD, mm | |||||
| Baseline | 19.00 ± 0.71 | 18.82 ± 1.52 | 18.95 ± 1.36 | 0.5843 | / |
| Follow-up | 18.39 ± 1.01 | 17.99 ± 4.87 | 17.01 ± 2.60 | 0.1392 | / |
| Changes | −0.61 ± 0.97 | −0.81 ± 5.08 | −1.96 ± 2.57 | 0.0307 | EM < HM |
| p-value | 0.0003 | <0.0001 | <0.0001 | ||
| AL, mm | |||||
| Baseline | 23.53 ± 0.40 | 25.06 ± 0.54 | 26.59 ± 0.59 | <0.0001 | EM < MIM/MOM < HM |
| Follow-up | 23.56 ± 0.41 | 25.15 ± 0.58 | 26.67 ± 0.62 | <0.0001 | EM < MIM/MOM < HM |
| Changes | 0.04 ± 0.10 | 0.08 ± 0.18 | 0.08 ± 0.13 | 0.0384 | EM < MIM/MOM, HM |
| p-value | 0.0253 | <0.0001 | <0.0001 | ||
| RT, μm | |||||
| Baseline | 280.08 ± 12.96 | 277.33 ± 11.05 | 273.99 ± 13.13 | 0.0530 | / |
| Follow-up | 278.29 ± 11.46 | 275.80 ± 10.74 | 267.13 ± 35.02 | 0.0052 | EM, MIM/MOM > HM |
| Changes | −0.79 ± 2.97 | −1.86 ± 3.32 | −6.94 ± 32.17 | 0.1585 | / |
| p-value | 0.1783 | <0.0001 | 0.0006 | ||
| GCC, μm | |||||
| Baseline | 108.92 ± 4.88 | 109.86 ± 6.04 | 109.19 ± 5.89 | 0.6318 | / |
| Follow-up | 108.88 ± 5.00 | 109.32 ± 6.54 | 105.25 ± 16.48 | 0.3053 | / |
| Changes | −0.14 ± 2.19 | −0.46 ± 2.99 | −3.66 ± 15.34 | 0.2452 | / |
| p-value | 0.7382 | <0.0001 | 0.0031 |
Data are presented as mean ± standard deviation.
Comparisons between the baseline and the follow-ups using the paired t-test. Comparison among the three groups were using the one-way ANOVA test with post-hoc test (Bonferroni).
EM, emmetropia; GCC, ganglion cell complex; MIM, mild myopia, MOM, moderate myopia; HM, high myopia; RT, retinal thickness; VD, macular vessel density.