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. 2021 Jun 8;9:643060. doi: 10.3389/fcell.2021.643060

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Copyright © 2021 Schaberg, Theocharidis, May, Lessmann, Schroeder and Faissner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sulfation of spinal cord progenitors had a minor influence on the cell cycle in the presence of EGF. The cell cycle lengths of control (black boxes) and chlorate-treated (gray boxes) spinal cord progenitors cultivated in the presence of EGF are shown for the first (A), second (B), third (C), fourth (D), fifth (E) and the sixth generation (F). In the third generation (C) the inhibition of sulfation led to a slightly slower cell division compared to untreated cells. In all other generations, the suppression of sulfation had no significant influence on the cell cycle length. *p ≤ 0.05 (Mann-Whitney U-test); control: N = 4; chlorate: N = 3.