Table 5.

Comparison among Association Models on Cross-sectional Hypertension using MESA Participants.

Association model	Sample Size	Case Number	OR per SD*	95% CI	p-value	AUC	NRI
AHI	2015	1365	1.22	[1.05, 1.42]	0.009	0.75	\
cSPPSG	923	615	1.26	[1.10, 1.45]	0.001	0.77	0.04
cSPHST	1242	820	1.26	[1.12, 1.42]	<0.001	0.77	0.03
cSPPSG, no lung function	1255	841	1.10	[0.99, 1.21]	0.072	0.75	0.04
cSPHST, no lung function	1697	1126	1.08	[1.00, 1.17]	0.042	0.75	0.01
FVCpp	3079	2147	0.80	[0.74, 0.87]	<0.001	0.75	0.04
FEV1pp	3074	2142	0.83	[0.77, 0.90]	<0.001	0.74	0.01

The number of participants varies across models due to missing data patterns. Case number is the number of individuals with hypertension in the specific association model.

¹ All NRIs are calculated in regard to AHI model

² The cut-off probability for categorizing hypertension is determined when Youden index is maximized

³ All prediction models adjust for age, sex, race/ethnicity, BMI, waist/hip ratio, smoking status and packet year

⁴ SD here all calculated from corresponding phenotype in SHHS.