Table 1.
Baseline characteristics of the study population
| Total (n=46) | Significant fibrosis (n=27) | Advanced fibrosis (n=18) | |
|---|---|---|---|
| Sex | |||
| Male | 27 (58.7) | 16 (40.7) | 10 (55.6) |
| Female | 19 (41.3) | 11 (59.3) | 8 (44.4) |
| Age (year) | 54.7±9.1 | 57.9±9.0 | 58.8±8.2 |
| BMI (kg/m2) | 29.4±4.5 | 29.8±5.1 | 30.0±4.9 |
| Fibrosis | |||
| F0 | 4 (8.7) | 0 | 0 |
| F1 | 15 (32.6) | 0 | 0 |
| F2 | 9 (19.6) | 9 (33.3) | 0 |
| F3 | 5 (10.9) | 5 (18.5) | 5 (27.8) |
| F4 | 13 (28.2) | 13 (48.2) | 13 (72.2) |
| NAS | 4.3±1.5 | 4.6±1.6 | 4.3±1.6 |
| Steatosis grade | |||
| 0 (<5%) | 1 (2.2) | 1 (3.7) | 1 (5.6) |
| 1 (5%-33%) | 14 (30.4) | 8 (29.7) | 7 (38.9) |
| 2 (33%-66%) | 17 (37.0) | 9 (33.3) | 4 (22.2) |
| 3 (>66%) | 14 (30.4) | 9 (33.3) | 6 (33.3) |
| Inflammation | |||
| 0 (no foci) | 2 (4.4) | 1 (3.7) | 1 (5.6) |
| 1 (<2 foci per ×200) | 20 (43.4) | 7 (25.9) | 5 (27.7) |
| 2 (2-4 foci per ×200) | 22 (47.8) | 17 (63.0) | 11 (61.1) |
| 3 (>4 foci per ×200) | 2 (4.4) | 2 (7.4) | 1 (5.6) |
| Ballooning | |||
| 0 (none) | 15 (32.6) | 7 (25.9) | 6 (33.3) |
| 1 (few balloon cells) | 26 (56.5) | 16 (59.3) | 10 (55.6) |
| 2 (many cells) | 5 (10.9) | 4 (14.8) | 2 (11.1) |
Values are presented as number (%) or mean±standard deviation.
BMI, body mass index; NAS, nonalcoholic fatty liver disease activity score.