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. 2021 Jun 8;12:625922. doi: 10.3389/fimmu.2021.625922

Table 1.

Overview of LDNs characterised by flow cytometry.

Disease: Disease Group LDN Markers: Control Group: Reference:
Identification: Systemic Lupus Erythematosus CD14-CD15+ PBMC N/A Denny et al. (25)
Rheumatoid Arthritis CD14- CD15+ CD10+ CD16+ PBMC N/A Wright et al. (30)
Late stage Lung Cancer CD66b+ PBMC N/A Shaul et al. (29)
Mycobacterium Tuberculosis CD14-CD15+ PBMC N/A Deng et al. (12)
Malaria CD66b+ CD15+ CD14- PBMC N/A Rocha et al. (18)
Psoriasis CD14- CD15+ CD10+ PBMC N/A Teague et al. (14)
Idiopathic Inflammatory Myopathy CD15+ CD10+ CD14- PBMC N/A Seto et al. (15)
Adult Onset Still’s Disease CD14- CD15+ CD10+ PBMC N/A Torres-Ruiz et al. (20)
Asthma CD14- CD66b+ CD16+ CD15+ PBMC N/A Fu et al. (33)
Phenotyping: Systemic Lupus Erythematosus ↑CD63 ↑Arg-1 Healthy LDNs Rahman et al. (7)
↑CD63 ↑Arg-1 ↑Lox1 ↑CD107a ↑CD95 ↑CD273 ↑CD274 SLE NDNs
Lung Adenocarcinoma ↑CD66b ↑CD11b ↑CD15 Adenocarcinoma NDNs* Liu et al. (3)
Cancer ↑CD66b ↑CD11b Cancer NDNs Sagiv et al. (17)
Human Immunodeficiency Virus ↑CD66b ↑CD63 ↑CD11b ↑CD15 ↑CD33 ↓CD16 ↓Arg1 HIV NDNs* Cloke et al. (13)
Mycobacterium Tuberculosis ↑CD15 ↑CD33 ↑CD66b ↓CD62L TB NDNs Deng et al. (12)
↑CD16 Healthy NDNs
Laparotomy (Lavage LDN) ↑CD63 ↑CD11b ↓CD62L Circulating NDNs Kanamaru et al. (9)
Psoriasis ↑CD15 ↓CD62L Psoriatic NDNs Teague et al. (14)
No difference Healthy LDNs
Asthma ↑CD11b ↑CD66b Asthma NDNs Fu et al. (33)
No difference Healthy LDNs

*Experiment contains healthy control LDN but no statistical comparison with disease groups.