Table 5.
Cases (17/140) of patients where metabolically avid lymph adenopathy in the axilla ipsilateral to COVID-19 vaccination led to change of management
| N | Age | Day p. vacci. | Vacc., site | Oncological diagnosis | SUVmax | History, imaging finding | Impact on management recommendation |
|---|---|---|---|---|---|---|---|
| 1# | 75 | 8 | M, left | Melanoma | 8.6 | Previously metastatic lymph nodes left cervical; new left axillary FDG-avid lymph node. | Additional sonography / fna |
| 2# | 69 | 13 | M, left | Melanoma | 4.4 | Metastatic melanoma with unclear primary; metabolic active lymph node left axilla. | Additional sonography / fna |
| 3# | 55 | 14 | M, left | Breast cancer | 10.1 | Operated right breast cancer with lymphadenectomy right axilla; new left axillary FDG-avid lymph node. | Additional sonography / fna |
| 4# | 49 | 15 | M, left | Melanoma | 5.5 | Melanoma resected left neck; new FDG-avid left axillary lymph node. | Additional sonography / fna |
| 5# | 76 | 27 | M, right | Melanoma | 5.3 | Melanoma resected left arm; new right axillary FDG-avid lymph node. | Additional sonography / fna |
| 6* | 77 | 2 | M, left | Melanoma | 10.0 | Melanoma resected left neck; new left axillary FDG-avid lymph node. | Additional sonography / fna |
| 7* | 53 | 3 | M, left | Melanoma | 11.6 | Melanoma resected left arm; new left axillary FDG-avid lymph node. | Earlier PET imaging restaging |
| 8* | 41 | 4 | PfB, left | Paraneoplastic syndrome | 14.4 | Highly FDG-avid left axillary lymph node. | fna of lymph nodes |
| 9* | 33 | 5 | PfB, left | Lymphoma | 17.3 | Unclear swelling of lymph nodes neck; highly FDG-avid left axillary lymph node. | fna of lymph nodes |
| 10* | 79 | 6 | PfB, right | Melanoma | 5.3 | Melanoma resected left shoulder; new right axillary FDG-avid lymph node. | Additional sonography / fna |
| 11* | 77 | 6 | PfB, left | Melanoma | 10.9 | Metastatic melanoma with unclear primary; FDG-avid left axillary lymph node. | Additional sonography / fna |
| 12* | 67 | 15 | M, left | Pharyngeal cancer | 9.5 | Extensive pharyngeal cancer with lymph node metastasis level I - V cervical plus left axillary. | Earlier PET imaging restaging |
| 13* | 73 | 17 | M, right | CLL | 7.4 | Mildly FDG-avid lymphadenopathy supra- and infradiaphragmal; imaging shows enhanced FDG-avidity in right axillary lymph nodes | Changing site of initially planned lymph node dissection |
| 14* | 64 | 23 | M, right | Melanoma | 2.6 | Melanoma metastasis right chest wall; new right axillary FDG-avid lymph node. | Additional sonography / fna |
| 15* | 44 | 26 | PfB, left | Melanoma | 8.2 | Metastatic melanoma; new left axillary FDG-avid lymph node. | Additional sonography / fna |
| 16* | 65 | 30 | PfB, left | Melanoma | 3.6 | Melanoma resected right neck; new left axillary FDG-avid lymph node. | Additional sonography / fna |
| 17* | 75 | 39 | PfB, right | Melanoma | 3.4 | Melanoma resected parietal right; new right axillary FDG-avid lymph node | Additional sonography / fna |
FDG, fluorodeoxyglucose; fna, fine needle aspiration; PET, positron emission tomography; vacci., vaccination; Vacc., vaccine (PfB = Pfizer-BioNTech; M = Moderna)
#Post 1. vaccination
*Post 2. vaccination