Table 1. The significantly differentially expressed CXCLs between HCC and normal liver tissues (Oncomine).
| Gene name | Fold change | P value | Sample size | Reference (PMID) | |
|---|---|---|---|---|---|
| HCC | Normal | ||||
| CXCL1 | -4.16 | 1.76E-20 | 102 | 72 | 12058060 |
| -6.54 | 8.33E-60 | 225 | 220 | 21159642 | |
| -3.60 | 4.65E-17 | 102 | 72 | 12058060 | |
| CXCL2 | -5.74 | 1.45E-07 | 35 | 10 | 17393520 |
| -7.40 | 2.59E-07 | 225 | 220 | 21159642 | |
| -2.27 | 9.36E-07 | 19 | 38 | 19098997 | |
| CXCL6 | 3.75 | 2.15E-07 | 19 | 38 | 19098997 |
| CXCL8 | 3.32 | 7.84E-06 | 19 | 38 | 19098997 |
| CXCL9 | 5.33 | 6.20E-17 | 19 | 38 | 19098997 |
| CXCL10 | 9.27 | 6.33E-17 | 19 | 38 | 19098997 |
| 5.93 | 1.78E-04 | 35 | 10 | 17393520 | |
| CXCL11 | 2.19 | 2.26E-06 | 19 | 38 | 19098997 |
| CXCL12 | -5.34 | 2.32E-93 | 225 | 220 | 21159642 |
| -2.39 | 4.32E-31 | 102 | 72 | 12058060 | |
| -4.04 | 4.43E-11 | 225 | 220 | 21159642 | |
| -4.23 | 3.82E-09 | 35 | 10 | 17393520 | |
| CXCL14 | -10.94 | 6.98E-154 | 225 | 220 | 21159642 |
| -9.67 | 1.24E-21 | 225 | 220 | 21159642 | |
| -12.90 | 1.96E-43 | 102 | 72 | 12058060 | |
| -13.98 | 6.81E-10 | 35 | 10 | 17393520 | |
Note: The screening threshold was set as: data type of mRNA, |fold change| of 2.0, P value of 0.05, and the rank of top 10% gene; PMID, PubMed Unique Identifier.