Table 2. Logistic Regression Models for the Association of Age, Sex, and Cardiovascular Disease History With Aspirin Use for Primary or Secondary Prevention in 7103 US Adults Aged 60 Years or Older With and Without Diabetes, NHANES 2011-2018.

Variable	History of diabetes, OR (95% CI)			No history of diabetes, OR (95% CI)
	Model 1a	Model 2	Model 3	Model 1	Model 2	Model 3
Age category, y
60-69	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]
70-79	0.99 (0.74-1.31)	0.95 (0.72-1.26)	0.95 (0.72-1.26)	1.67 (1.39-2.02)	1.50 (1.23-1.83)	1.50 (1.23-1.83)
≥80	0.88 (0.63-1.23)	0.84 (0.59-1.20)	0.87 (0.61-1.26)	1.91 (1.53-2.40)	1.54 (1.20-1.98)	1.59 (1.24-2.04)
P value for trends	.58	.76	.98	<.001	<.001	<.001
Sex
Male	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]
Female	0.61 (0.46-0.79)	0.63 (0.49-0.82)	0.63 (0.48-0.83)	0.81 (0.70-0.95)	0.87 (0.74-1.03)	0.89 (0.75-1.05)
CVD historyb
Low risk	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]
High risk	1.82 (0.67-4.96)	1.76 (0.68-4.59)	1.69 (0.65-4.39)	2.60 (1.73-3.93)	2.51 (1.66-3.79)	2.46 (1.63-3.71)
History of CVD	3.14 (1.17-8.43)	2.93 (1.14-7.49)	3.00 (1.18-7.59)	9.27 (6.08-14.12)	8.23 (5.41-12.53)	8.27 (5.54-12.34)

Abbreviations: CVD, cardiovascular disease; MI, myocardial infarction; NHANES, National Health and Nutrition Examination Survey; OR, odds ratio.

^aModel 1, unadjusted; Model 2, adjusted for age, sex, race/ethnicity, education, CVD risk status (all covariates included except the variable used to stratify participants in each of the respective models above); Model 3, Model 2 plus body mass index.

^bLow risk, no CVD risk factors; high risk, 1 or more CVD risk factors. CVD risk factors include family history of MI, obesity, hypertension, smoking, albuminuria, and hypercholesterolemia.