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. 2019 Nov 29;3:20. doi: 10.1186/s41824-019-0066-2

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 70 — ¹⁸F-NaF, breast cancer staging. Clinical history: 55 y.o. woman recently diagnosed with breast cancer (ductal adenocarcinoma, ER+, PR, and HER2 neg), asymptomatic. PET/CT findings: multiple foci of increased tracer uptake consistent with skeletal metastatic spread (a MIP). Note the heterogeneity of the CT appearance in this patient: some lesions are osteolytic (b), others are sclerotic (c) or do not show any CT anomaly (d)