Skip to main content
. 2021 May 1;49(W1):W589–W596. doi: 10.1093/nar/gkab300

Figure 2.

Figure 2.

The refinement of four CASP14 targets using the ReFOLD3 protocol. In the left panels, the initial structures were coloured by the per-residue accuracy score produced by ModFOLD8. In the middle panels, superposition of the best predicted 3D server model selected by ModFOLD8 or the starting model provided by CASP in the refinement category (cyan), the top 3D model generated by ReFOLD3 (magenta) and native structure (green). In the right panels, GDT_TS plots for the comparison of the original 3D model (cyan) with the top 3D model generated by ReFOLD3 (magenta). (A) CASP14 regular TBM-hard target T1030: RaptorX_TS1 versus McGuffin_TS1, a GDT_TS improvement from 39.84 to 43.77. (B) CASP14 regular FM/TBM target T1035 domain 1: tFOLD-lDT_TS3 versus McGuffin_TS1, a GDT_TS improvement from 48.28 to 50.00. (C) CASP14 refinement FM target R10909: starting model versus McGuffin_TS1, a GDT_TS improvement from 65.61 to 67.06 (D) CASP14 refinement TBM-easy target R1091-D1: starting model versus McGuffin TS1, a GDT_TS improvement from 79.21 to 81.78. Images are created using PyMOL (http://www.pymol.org). GDT_TS plots are from https://www.predictioncenter.org/casp14/.