Table 2.
Adjusted ORs and 95% CIs for incident any, early and late AMD at visit 5, by tertiles of Western and prudent dietary pattern scores using average visit 1 and visit 3 diet data (n=1278)
| Any AMD | Tertile 1 | Tertile 2 | Tertile 3 | P trend* |
|---|---|---|---|---|
| Western pattern | n=426 | n=426 | n=426 | |
| Events n† | 49 | 50 | 45 | |
| Model 1‡ | Reference | 1.19 (0.76 to 1.87) | 1.43 (0.83 to 2.46) | 0.287 |
| Model 2§ | Reference | 1.31 (0.78 to 2.20) | 1.69 (0.88 to 3.25) | 0.144 |
| Prudent pattern | n=426 | n=426 | n=426 | |
| Events n | 48 | 54 | 42 | |
| Model 1 | Reference | 1.11 (0.72 to 1.72) | 0.90 (0.56 to 1.46) | 0.623 |
| Model 2 | Reference | 1.24 (0.73 to 2.11) | 0.84 (0.49 to 1.46) | 0.555 |
| Incident Early AMD¶ | Tertile 1 | Tertile 2 | Tertile 3 | P trend |
| Western pattern | n=417 | n=412 | n=407 | |
| Events n | 44 | 40 | 33 | |
| Model 1 | Reference | 1.03 (0.64 to 1.66) | 1.10 (0.61 to 2.00) | 0.882 |
| Model 2 | Reference | 1.24 (0.71 to 2.14) | 1.41 (0.69 to 2.88) | 0.493 |
| Prudent pattern | n=411 | n=410 | n=415 | |
| Events n | 37 | 44 | 36 | |
| Model 1 | Reference | 1.17 (0.73 to 1.89) | 1.00 (0.59 to 1.68) | 0.858 |
| Model 2 | Reference | 1.38 (0.76 to 2.52) | 0.97 (0.53 to 1.78) | 0.996 |
| Incident late AMD | <Median | ≥Median | - | P trend |
| Western pattern | n=639 | n=639 | - | |
| Events n | 9 | 18 | - | |
| Model 1** | Reference | 3.44 (1.33 to 8.87) | - | 0.014 |
| Model 2 | Reference | 3.00 (1.06 to 8.47) | - | 0.005 |
| Prudent pattern | n=639 | n=639 | - | |
| Events n | 17 | 10 | - | |
| Model 1** | Reference | 0.51 (0.22 to 1.18) | - | 0.054 |
| Model 2 | Reference | 0.43 (0.18 to 1.05) | - | 0.012 |
P-trend was computed using the continuous diet patterns score.
Events=Total cases in the tertile group.
Model 1: Adjusted for age, race, education, daily energy intake (kcal) and smoking status.
Model 2: Model 1 further adjusted for inverse probability weights.
The n=1236 because participants with early AMD at visit 3 and/or those who developed incident late AMD by visit 5 were excluded from this analysis.
There were no cases of African–American participants with late AMD; therefore, the model for risk of late AMD could not be adjusted for race.
AMD, age-related macular degeneration.