TABLE 1.
Compound | CHIKV |
SFV |
||
---|---|---|---|---|
EC50 (μM)a | CC50 (μM)b | EC50 (μM) | CC50 (μM) | |
FHA | 0.7 ± 0.08 | >250 | 3.9 ± 3.5 | >250 |
FHNA | 1.2 ± 0.03 | >250 | 5.2 ± 3.2 | >250 |
CHVB-066 | 0.6 ± 0.1 | 25 | NAc | 25 |
CHVB-032 | 3.4 ± 0.3 | >100 | NA | >100 |
MADTP-372 | 2.7 ± 0.2 | >100 | NA | >100 |
Sinefungin | 184.9 ± 38.4 | >1,000 | NA | >1,000 |
EC50, the concentration of a compound that reduces virus-induced CPE by 50%.
CC50, the concentration of a compound that reduces cell viability by 50%.
NA, not active.