Table 1.

Patient group characteristics.

	Pre-pouch ileitis + pouchitis [n = 66]	Pouchitis alone [n = 66]	p-value
Age [years]	50 [36, 64]	50 [33, 57]	0.11
Age of IBD onset [years]	27 [17, 36]	25 [17, 34]	0.48
Male sex	41 [62.1]	41 [62.1]	1.00
Preoperative diagnosis
UC	41 [62.1]	41 [62.1]	1.00
IBD-U	25 [37.9]	25 [37.9]
Disease extent
Proctitis [Montreal E1]	5 [7.6]	1 [1.5]	0.27
Left-sided colitis [Montreal E2]	9 [13.6]	11 [16.7]
Pancolitis [Montreal E3]	52 [78.8]	54 [81.8]
Family history of IBD	19 [28.8]	20 [30.3]	0.85
Primary sclerosing cholangitis	5 [7.6]	5 [7.6]	1.00
Backwash ileitis	10 [15.2]	11 [16.7]	0.82
Pre-colectomy immunomodulator use	53 [80.3]	43 [65.2]	0.05
Pre-colectomy biologic use	36 [54.6]	37 [56.1]	0.86
Indication for surgery
Medically refractory disease	55 [83.3]	62 [93.9]	0.06
Dysplasia or cancer	11 [16.7]	4 [6.1]
IPAA stages
Two	43 [65.2]	36 [54.6]	0.21
Three	23 [34.8]	30 [45.4]
Time from ileostomy closure to pre-pouch ileitis/pouchitis diagnosis [months]	33 [5, 67]	14 [6, 38]	0.004

All values expressed as median [interquartile range] or n [%].

IBD, inflammatory bowel disease; UC, ulcerative colitis; IBD-U, IBD-unclassified; IPAA, ileal pouch-anal anastomosis.