Table 2.
Univariable analysis | Multivariable analysis | |||
---|---|---|---|---|
HR [95% CI] | p-value | HR [95% CI] | p-value | |
Age | 1.0 [0.9–1.0] | 0.49 | ||
Male | 1.0 [0.5–2.0] | 1.00 | ||
UC diagnosis | 1.0 [0.5–2.1] | 0.91 | ||
Age of IBD onset | 1.0 [0.9–1.0] | 0.44 | ||
Pancolitis | 0.5 [0.2–0.9] | 0.03 | 0.5 [0.3–1.0] | 0.06 |
Family history of IBD | 1.2 [0.6–2.6] | 0.59 | ||
Primary sclerosing cholangitis | 1.5 [0.5–5.0] | 0.50 | ||
Backwash ileitis | 0.9 [0.3–2.5] | 0.81 | ||
Pre-colectomy IMM use | 2.1 [0.8–5.5] | 0.12 | ||
Pre-colectomy biologic | 1.1 [0.5–2.2] | 0.82 | ||
Disease activity as IPAA indication | 1.2 [0.4–3.4] | 0.73 | ||
Two-stage IPAA | 1.4 [0.6–3.8] | 0.43 | ||
Pre-pouch ileitis | 3.9 [1.8–8.6] | 0.0005 | 3.8 [1.8–8.3] | 0.0007 |
IBD, inflammatory bowel disease; UC, ulcerative colitis; IPAA, ileal pouch-anal anastomosis, IMM, immunomodulator; HR, hazard ratio; CI, confidence interval; CD, Crohn’s disease.
Bold numbers represents statistically significant results.