Figure 4.

IRs of herpes zoster infection by time intervals in the Overall Cohort for [A] tofacitinib all doses, [B] tofacitinib PD 5 mg BID, and [C] tofacitinib PD 10 mg BID groups. PD groups [the average daily tofacitinib dose levels in the entire UC clinical programme] were based on the average total daily dose of tofacitinib during tofacitinib treatment: PD 5 mg BID, an average total daily dose <15 mg; PD 10 mg BID, an average total daily dose ≥15 mg. BID, twice daily; CI, confidence interval; IR, incidence rate; N, total number of patients in the treatment group; n, number of patients with events; PD, predominant dose; UC, ulcerative colitis.