Average change in (A) whole-body fat area and (B) whole-body lean tissue area between baseline and 9 days post-MI. Fat area decreased all groups, but lean tissue area decreased only in MI mice (main effect of MI: p < .001), and this change was greatest for β3-AR antagonist treated MI mice (−18.3%, p ≤ .001). * denotes p ≤ .05 between baseline and 9 days post-MI. β3-AR, beta 3-adrenergic receptor; MI, myocardial infarction