. 2021 May 23;13(5):e15194. doi: 10.7759/cureus.15194

Table 4. Study characteristics of published studies about radiosurgery and the comparison between RGZ and DREZ targets in trigeminal neuralgia .

^aThis study reports a significant statistical difference in the target zone between DREZ and RGZ regarding pain control (p=0.003) and lower complication rates (p=0.009).

^bTreatment success is based on the percent of patients who had excellent pain control at the final visit.

^cTreatment success is based on the percent of patients who reported having BNI I, II, IIIa, and IIIb after SRS.

Abbreviations: BNI, Barrow Neurological Institute; DREZ, dorsal root entry zone; FU, follow-up; GK, gamma knife; RGZ, retrogasserian zone; SRS, stereotactic radiosurgery.

Reference	Type of study	Sample size (N)	Radiosurgery technology	Total dose (Gy)		Treatment success, n (%)		Complications, n (%)		FU (months)
Matsuda et al.^a 2008 [12]	Retrospective	100	GK	RGZ	DREZ	RGZ	DREZ	RGZ	DREZ	RGZ	DREZ
Matsuda et al.^a 2008 [12]	Retrospective	100	GK	80-90	80	42.9^b	41.2^b	26.5	11.8	25±15	47±24
Park et al. 2010 [13]	Retrospective	39	GK	83-90	80-90	93.8^c	87^c	0	13.1	16.5	32.8
Xu et al. 2014 [14]	Retrospective	99	GK	80	80	82	60	53	25	33	33
Current series 2021	Retrospective	49	GK	80-94	80-96	78.1^c	70.6^c	31.3	35.5	36.0	51.0