Table 5. Normalized In Silico Kappas by Year^a.

NISK	Year 1 (Vd2RV)	Year 2 (Vd2RV)
TA NISK	0.95 (0.89-0.96)	0.93 (0.87-0.94)
SSA NISK	0.54 (0.45-0.60)	0.63 (0.51-0.70)

Abbreviations: NISK, normalized in silico kappa; SSA, sessile serrated adenoma; TA, tubular adenoma.

^aThis tables shows the NISK for both TA and SSA. The numbers in the brackets represent the 95% confidence interval of the variance due to rate variance (Vd2RV); this was calculated by the bootstrap method (see SDC Appendix D, available at: http://links.lww.com/QMH/A51, for details).