Table 1.
Demographics and Baseline Characteristics (Seronegative).*
| Placebo (N=752) | REGEN-COV 1200 mg SC (N=753) | Total (N=1505) | |
|---|---|---|---|
|
| |||
| Age — yr | |||
| Mean (range) | 42.7 (12–92) | 43.2 (12–87) | 42.9 (12–92) |
| ≥50 — no. (%) | 280 (37.2) | 294 (39.0) | 574 (38.1) |
| Sex — no. (%) | 358 (47.6) | 333 (44.2) | 691 (45.9) |
| Race — no. (%) | |||
| White | 635 (84.4) | 653 (86.7) | 1288 (85.6) |
| Black or African American | 78 (10.4) | 62 (8.2) | 140 (9.3) |
| Asian | 19 (2.5) | 23 (3.1) | 42 (2.8) |
| American Indian or Alaska Native | 4 (0.5) | 3 (0.4) | 7 (0.5) |
| Native Hawaiian or Pacific Islander | 2 (0.3) | 1 (0.1) | 3 (0.2) |
| Other | 14 (1.9) | 11 (1.5) | 25 (1.7) |
| Ethnicity — no. (%) | |||
| Hispanic or Latino | 319 (42.4) | 291 (38.6) | 610 (40.5) |
| Not Hispanic or Latino | 428 (56.9) | 459 (61.0) | 887 (58.9) |
| Other | 5 (0.7) | 3 (0.4) | 8 (0.5) |
| Mean weight — kg | 81.2±19.72 | 81.3±19.92 | 81.3±19.81 |
| Body-mass index† | |||
| Mean | 28.5±6.28 | 28.9±12.35 | 28.7±9.79 |
| >30 — no. (%) | 243 (32.3) | 260 (34.5) | 503 (33.4) |
| Participants with any high-risk factor for Covid-19 — no. (%) | 221 (29.4) | 238 (31.6) | 459 (30.5) |
| ≥65 years of age | 55 (7.3) | 76 (10.1) | 131 (8.7) |
| Body-mass index† ≥35 kg/m2 | 104 (13.8) | 99 (13.1) | 203 (13.5) |
| Chronic kidney disease | 11 (1.5) | 17 (2.3) | 28 (1.9) |
| Diabetes | 45 (6.0) | 58 (7.7) | 103 (6.8) |
| Immunosuppressive disease | 2 (0.3) | 5 (0.7) | 7 (0.5) |
| Receiving immunosuppressive treatment | 11 (1.5) | 4 (0.5) | 15 (1.0) |
| ≥55 years of age with CVD, hypertension, or COPD | 90 (12.0) | 99 (13.1) | 189 (12.6) |
| Total no. of households | 686 | 679 | 1209 |
| Number of households by size — no. (%)‡ | |||
| 1 | 503 (73.3) | 486 (71.6) | 989 (81.8) |
| 2 | 136 (19.8) | 146 (21.5) | 172 (14.2) |
| 3 | 30 (4.4) | 30 (4.4) | 31 (2.6) |
| 4 | 13 (1.9) | 13 (1.9) | 13 (1.1) |
| >4 | 4 (0.6) | 4 (0.6) | 4 (0.3) |
| Participants with an index case participating in study COV-2067 — no. (%) | 186 (24.7) | 187 (24.8) | 373 (24.8) |
*
Plus-minus values are means ±SD. COPD denotes chronic obstructive pulmonary disease, CVD cardiovascular disease, and SC subcutaneous.
†
The body-mass index is the weight in kilograms divided by the square of the height in meters.
‡
Household size is calculated by counting the seronegative study participants in Part A. Percentages are based on the number of households as the denominator, instead of the number of participants.