Table 2.
Plume and Particle Characteristics for BDP/FF/GB and BDP/FF
| BDP/FF/GB | BDP/FF | ||||
|---|---|---|---|---|---|
| Mass (g) | 0.073 | 0.058 | |||
| Angle (°) | 21.24 | 15.61 | |||
| Velocity (m/s) | 21.0 (at 10 mm) | 11.4 (at 10 mm) | |||
| 6.0 (at 100 mm) | 5.1 (at 100 mm) | ||||
| Duration (ms) | 229.4 | 169.0 | |||
| API | BDP | FF | GB | BDP | FF |
| MMAD (μm) | 1.1 | 1.1 | 1.1 | 1.3 | 1.3 |
| GSD | 2.0 | 2.0 | 2.0 | 2.4 | 2.1 |
| FPF (% of DD) | 43 | 44 | 42 | 42 | 42 |
| DD (μg) | 87 | 5 | 11 | 85 | 5 |
API, active pharmaceutical ingredient; BDP, beclomethasone dipropionate; DD, delivered dose; FF, formoterol fumarate; FPF, fine particle fraction; GB, glycopyrronium bromide; GSD, geometric standard deviation; MMAD, mass median aerodynamic diameter.