Skip to main content
. 2021 Jun 15;2021:6644238. doi: 10.1155/2021/6644238

Figure 6.

Figure 6

SS-31 prevents mitochondrial dysfunction in CS-induced mouse lung. (a–d) Protein levels of OPA1, MFF (a, b), and cytochrome c (c, d) in lungs were evaluated by western blot following exposure to CS with or without SS-31 pretreatment. GAPDH or COX IV was used as a loading control (n = 3 per group). ∗∗P < 0.01 and ∗∗∗P < 0.001 vs. control; #P < 0.05 vs CS. Abbreviations: COX IV: cytochrome c oxidase IV; CS: cigarette smoke; Cyt c: cytochrome c; GAPDH: glyceraldehyde 3-phosphate dehydrogenase; MFF: mitochondrial fission factor; mit: mitochondrion; OPA1: optic atrophy 1; SS-31 (H): high-dose SS-31 (5 mg/kg); SS-31 (L): low-dose SS-31 (2.5 mg/kg).