Table 2.
Brain functional connectivity between ON patients and HCs identified by NBS analysis.
| Connectivity | t value | P NBS |
|---|---|---|
| ROL.L to DCG.L | 6.026 | <0.05 |
| ROL.L to DCG.R | 5.747 | <0.05 |
| ROL.R to DCG.L | 5.239 | <0.05 |
| ROL.R to AMYG.R | 5.212 | <0.05 |
| SFG med.R to CRBL_Crus6_L | 5.205 | <0.05 |
| INS.L to DCG.L | 6.066 | <0.05 |
| INS.L to DCG.R | 5.169 | <0.05 |
| INS.L to AMYG.L | 5.284 | <0.05 |
| INS.L to SPG.L | 5.129 | <0.05 |
| INS.R to DCG.L | 5.454 | <0.05 |
| INS.R to IPL.R | 5.365 | <0.05 |
| INS.R to ANG.L | 5.071 | <0.05 |
| INS.R to ANG.R | 5.220 | <0.05 |
| INS.R to STG.L | 5.085 | <0.05 |
| SMG.L to PAL.R | 5.444 | <0.05 |
| SMG.R to CRBL_6_L | 5.257 | <0.05 |
Notes: NBS: T > 3.92, P < 0.05 and 5,000 permutations, P < 0.05 indicates a significant difference between the groups. Abbreviation: ON: optic neuritis; HCs: healthy controls; ROL: rolandic operculum; SFGmed: superior frontal gyrus, medial; INS: insula; DCG: median cingulate and paracingulate gyri; AMYG: amygdala; SPG: superior parietal gyrus; IPL: inferior parietal gyrus, but supramarginal and angular gyri; SMG: supramarginal gyrus; ANG: angular gyrus; PAL: lenticular nucleus, pallidum; STG: superior temporal gyrus; CRBLCrus1: cerebellum_Crus1; CRBL 6: cerebellum_Crus6; L: left hemisphere; R: right hemisphere.