Table 4.
Collaborations of AI organization with pharmaceutical companies
| S. no. | Company | Role of AI | Collaboration with the pharmaceutical company | Platform developed/Clinical trial candidates |
|---|---|---|---|---|
| 1 | Numerate | A platform for AI-based drug design against oncology and gastroenterology | Takeda | Drug candidate S48168 in Phase 1 clinical trial against Ryanodine receptor 2 |
| 2 | Numerate | A platform for AI-based drug design against oncology and gastroenterology | Servier | Drug development for oncology, gastroenterology and central nervous system disorders |
| 3 | Atomwise | A platform for AI-based structure modelling | Lilly | Drug candidate BBT-401 in Phase 2 clinical trial |
| 4 | Atomwise | A platform for AI-based structure modelling | Bridge Biotherapeutics | Expansion of Pellino Inhibitor Pipeline; BBT-401 in Phase-2a clinical trial |
| 5 | Benevolent AI | AI-enabled Judgement Augmented Cognition System (JACS) to develop novel clinical candidate against neurodegenerative diseases | Janssen | New range of drug molecules to be developed through this collaboration |
| 6 | Benevolent AI | AI enable platforms to develop novel clinical candidate against chronic kidney diseases | AstraZeneca | Drug candidate Placebo in Phase 2b clinical trial as a drug candidate for chronic kidney disease |
| 7 | Exscientia | A platform for AI-based drug discovery and lead optimization | Sanofi | Research in obsessive–compulsive disorder, Drug candidate DSP-1181 in Phase I clinical trial. Developed Centaur Chemist™ platform for AI-based drug discovery |
| 8 | IBM Watson Health | Provide a platform for clinical and health-related data research | Pfizer | Fast-tracking drug discovery research in immuno-oncology |
| 9 | IBM Watson Health | Provide a platform for clinical and health-related data research | Novartis | Real-time monitoring of patients to improve breast cancer patient outcome |
| 10 | Microsoft | A platform for image processing and cell and gene-based therapeutics | Novartis | Establishing an AI Innovation lab to transform the drug discovery process and its commercialization |
| 11 | Owkin | Provide a platform for a clinical trial based on ML technology | Roche | Developed Owkin’s Studio platform using AI technology |
| 12 | Sensyne health | A platform for clinical AI technology | Bayer | Developed Sensyne Health’s proprietary clinical AI technology platform |
| 13 | XtalPi | A platform for Target identification and validation based on QM and ML algorithm | Pfizer | Prediction and Optimization of crystalline forms of drug candidates for early drug screening |
| 14 | BioXcel therapeutics | A platform for the drug discovery application using AI technology | Pfizer | Drug candidate BXCL501-in Phase 3 clinical trial Drug candidate BXCL701-in Phase 2 clinical trial |