Table 2.
Poor outcomes with intraventricular hemorrhage at 18 months of corrected age
| Outcome | Placebo | rhEPO | RR (95% CI) | p value |
|---|---|---|---|---|
| Primary outcome | ||||
| Death | 16/140 (11.4) | 9/134 (6.7) | 0.558 (0.238–1.310) | 0.176 |
| Disability | 21/124 (16.9) | 11/125 (8.8) | 0.473 (0.218–1.029) | 0.055 |
| Death + disability | 37/140 (26.4) | 20/134 (14.9) | 0.488 (0.267–0.895) | 0.019 |
| Secondary outcomea | ||||
| Cerebral palsy | 8/124 (6.5) | 4/125 (3.2) | 0.479 (0.141–1.635) | 0.231 |
| MDI < 70 | 19/124 (15.3) | 9/125 (7.2) | 0.429 (0.186–0.989) | 0.043 |
| Deafness | 1/124 (0.8) | 2/125 (1.6) | 2.000 (0.179–22.344) | 0.566 |
| Blindness | 2/124 (1.6) | 0/125 (0) | 0.984 (0.962–1.006) | 0.154 |
Data are presented as n/N (%) unless otherwise indicated. Disability is defined as surviving infants with one or more of the following complications: cerebral palsy, MDI < 70, blindness, or deafness. p < 0.05 was considered statistically significant
CI confidence interval, MDI Mental Developmental Index, rhEPO recombinant human erythropoietin, RR relative risk
aOne infant with more than one disability could be counted repeatedly