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. 2021 Jun 22;11:13062. doi: 10.1038/s41598-021-91201-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Bar graphs depicting the percentage of reclassifications into lower- and higher-risk groups when combining the 11-gene score with SAPS 3 using net reclassification improvement index in those patients with samples drawn within 24 h of emergency department arrival, evaluating (a) 60-day mortality in all comers, (b) in-hospital mortality in all comers, (c) 60-day mortality in shock patients, and (d) 60-day mortality in the subgroup of patients with primary prognostic determinant of MODS and/or ARDS. Correct reclassification is indicated by survivors who were reclassified to lower-risk group and deaths who were reclassified to high-risk group.