Table 2.
Characteristics of subjects in the top quartile vs bottom quartiles of 11-gene scores.
| Bottom quartiles* (n = 55) | Top quartile* (n = 15) | P-value | |
|---|---|---|---|
| Median age (IQR) | 71 (61–80) | 67 (61–81) | 0.88 |
| % Female | 38% | 47% | 0.57 |
| Race | |||
| White | 39 (71%) | 13 (87%) | 0.32 |
| Black/African American | 4 (7%) | 0 (0%) | 0.57 |
| Asian/Pacific Islander | 5 (9%) | 2 (13%) | 0.64 |
| Other/unknown | 7 (13%) | 0 (0%) | 0.33 |
| Infection | 36 (65%) | 11 (73%) | 0.73 |
| Median SAPS 3 (IQR) | 59 (51–73) | 64 (59–79) | 0.14 |
| Median APACHE II (IQR) | 20 (17–25) | 26 (21–31) | 0.02 |
| Shock | 22 (40%) | 11 (73%) | 0.04 |
| Primary determinant of prognosis | |||
| MODS and/or ARDS | 16 (29%) | 6 (40%) | 0.53 |
| Mixed | 20 (36%) | 6 (40%) | 1 |
| Comorbidities | 19 (35%) | 3 (20%) | 0.36 |
| 60-day mortality | 8 (15%) | 6 (40%) | 0.06 |
*Top quartile cutoff was calculated based on all 11-gene scores (all 165 patients).