Table 3.

Correlation of cerebrospinal fluid (CSF) and plasma soluble triggering receptor expressed on myeloid cells 2 (sTREM2) with Alzheimer’s disease (AD) biomarkers in patients with AD continuum (amyloid-positive group) (N=47).

		CSF sTREM2		Plasma sTREM2
		R	P-value	R	P-value
CSF	Aβ42	– 0.152	0.281	0.128	0.365
	P-tau S199	0.254	0.069	-0.288	0.038
	T-tau	0.455	< 0.001	-0.227	0.110
	Aβ42/P-tau S199	– 0.331	0.017	0.316	0.022
	NfL	0.018	0.901	0.457	<0.001
Plasma	NfL	0.323	0.021	0.349	0.012
	NRGN	0.080	0.584	0.126	0.389
	Telomere	– 0.072	0.610	– 0.146	0.303
	Age	0.080	0.574	0.345	0.012

Linear regression analyses were used to demonstrate a correlation between biomarkers.

NfL neurofilament light chain, NRGN neurogranin.