Table 1.

Mobile element insertions and structural variants involving mobile elements identified in four longitudinal breast cancer patients.

Patient	Locus	Variant	Region	Genes affected	Present before first tumor timepoint
Patient 1	1:186,755,400	Alu (non-classical insertion)	Intergenic		Yes
	1:29,089,030	Alu-Alu associated deletion (23 kb)	Exon	YTHDF2	Yes
	2:62,111,770	SVA insertion	Intronic	CCT4	No
	17:11,974,341/22:48,343,831	Alu-associated translocation	Exon	MAP2K4	Yes
Patient 2	2:15,168,000	Alu (non-classical insertion)	Intergenic		Yes
	8:99,227,400	L1 insertion	Exon	NIPAL2	Yes
	13:19,866,150	L1 insertion	Intronic	ANKRPD26P3	Yes
Patient 3	6:105,643,750	Alu-Alu associated deletion	Intergenic		Yes
Patient 4	10:67,431,020	Alu insertion	Intergenic		Yes
	11:81,149,160	L1-associated deletion	Intergenic		Yes
	19:23,124,500	SVA insertion	Intergenic		No

Insertion or variant sites found within genes (exonic or intronic) are indicated in the “Genes affected” column. Insertion events described as “non-classical insertions” do not show any hallmarks of L1-mediated insertion events.