Table 1.
Sample characteristics.
| KL-VShet carriers | KL-VShet non-carriers | p value | |
|---|---|---|---|
| ADNI, all | |||
| N | 144 | 407 | |
| Age | 71.29 (6.61) | 71.39 (6.72) | 0.880 |
| Sex, F:M | 76:68 | 206:201 | 0.727 |
| Diagnosis, CN:MCI:ADD | 102:34:8 | 245:122:40 | 0.059 |
| Education, years | 16.20 (2.50) | 16.65 (2.51) | 0.065 |
| MMSE | 28.17 (2.43) | 28.11 (2.82) | 0.819 |
| ApoE ε4 status, neg:pos | 90:54 | 255:152 | 1.000 |
| Global amyloid-PET, CL | 28.85 (37.94) | 32.28 (40.30) | 0.373 |
| Amyloid-PET status, neg:pos | 89:55 | 232:175 | 0.365 |
| Longitudinal subsample | |||
| N | 52 | 148 | |
| Age | 70.93 (5.76) | 71.43 (6.56) | 0.631 |
| Sex, F:M | 28:24 | 69:79 | 0.462 |
| Diagnosis, CN:MCI:ADD | 36:12:4 | 77:55:16 | 0.097 |
| Education, years | 15.85 (2.58) | 16.56 (2.51) | 0.081 |
| MMSE | 28.00 (2.59) | 27.92 (2.48) | 0.841 |
| ApoE ε4 status, neg:pos | 25:27 | 81:67 | 0.506 |
| Global amyloid-PET, CL | 45.01 (41.44) | 42.73 (42.59) | 0.739 |
| Amyloid-PET status, neg:pos | 22:30 | 61:87 | 1.000 |
| Tau-PET follow-up, years | 1.54 (0.75) | 1.66 (0.80) | 0.330 |
CN cognitively normal, MCI mild cognitive impairment, ADD Alzheimer’s disease dementia, F female, M male, MMSE Mini-Mental State Examination, neg negative, pos positive, CL centiloid.