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. 2021 Jun 23;135:104605. doi: 10.1016/j.compbiomed.2021.104605

Table 4.

Overview of deep learning approaches for automated COVID-19 diagnosis.

Reference Task Modality Method Total No. Of Images No. Of Images From COVID-19 Cases Accuracy (%) Remarks
Wang and Wong (2020) [120] Automatic COVID-19 diagnosis CXR CNN 13,975 358 93.3 COVID-Net has been proposed.
Narin et al. (2020) [113] Automatic COVID-19 diagnosis CXR CNN 100 50 98 The pre-trained ResNet50 model provides the highest classification performance.
Hemdan et al. (2020) [114] Automatic COVID-19 diagnosis CXR CNN 75 25 90 The VGG19 and DenseNet201 models showed a good and similar performance.
Ghoshal and Tucker (2020) [115] Estimating uncertainty and interpretability in deep learning for COVID-19 diagnosis CXR BCNN 5941 68 89 Experiment has shown a strong correlation between model uncertainty and accuracy of prediction.
Apostolopoulos and Mpesiana (2020) [242] Automatic COVID-19 diagnosis CXR CNN 1442 224 96.78 The MobileNet v2 effectively distinguished the COVID-19 cases from viral and bacterial pneumonia cases.
Apostolopoulos et al. (2020) [117] Automatic classification of pulmonary diseases CXR CNN 3905 455 99.18 Mobile Net has been used for transfer learning.
Abbas et al. (2020) [243] Automatic COVID-19 diagnosis CXR CNN 196 105 95.12 A deep CNN, called Decompose, Transfer, and Compose (DeTraC) has been validated.
Afshar et al. (2020) [244] Automatic COVID-19 diagnosis CXR CNN 13,975 358 95.7 COVID-CAPS including several Capsule and convolutional layers has been proposed.
Chowdhury et al. (2020) [245] Automatic COVID-19 diagnosis CXR CNN 2876 190 98.3 SqueezeNet outperforms AlexNet, ResNet18 and DenseNet201.
Oh et al. (2020) [121] Automatic COVID-19 diagnosis CXR CNN 15,043 180 91.9 A patch-based deep neural network architecture that can be stably trained with small data set has been proposed.
Rajaraman et al. (2020) [246] Automatic COVID-19 diagnosis CXR CNN 16,700 313 99.01 The best performing models are iteratively pruned to identify optimal number of neurons in the convolutional layers to reduce complexity and improve memory efficiency.
Luz et al. (2020) [247] Automatic COVID-19 diagnosis CXR CNN 13,800 183 93.9 The proposed model has about 30 times parameters fewer than the baseline literature model, 28 and 5 times parameters fewer than the popular VGG16 and ResNet50 architectures, respectively.
Tartaglione et al. (2020) [248] Automatic COVID-19 diagnosis CXR CNN 584 405 95 Possible obstacles in successfully training a deep model have been highlighted.
Hammoudi et al. (2020) [249] Automatic COVID-19 diagnosis CXR CNN 5863 95.72 The DenseNet169 architecture has reached the best performance.
Khan et al. (2020) [250] Automatic COVID-19 diagnosis CXR CNN 1300 284 89.5 CoroNet, a deep CNN based model, has been proposed.
Santosh et al. (2020) [251] Automatic COVID-19 diagnosis CXR CNN 6756 73 99.96 The Truncated Inception Net deep learning model has been proposed.
Pereira et al. (2020) [252] Automatic COVID-19 diagnosis CXR CNN 1144 90 A macro-avg F1-Score of 0.65 using a multi-class approach and an F1-Score of 0.89 for the COVID-19 identification in the hierarchical classification scenario have been achieved.
Murphy et al. (2020) [253] Automatic COVID-19 diagnosis CXR CNN 25,146 416 An AUC of 0.81 has been achieved. The performance of an AI system in the detection of COVID-19 is comparable with that of six independent readers.
Ozturk et al. (2020) [254] Automatic COVID-19 diagnosis CXR CNN 1127 127 98.08 The DarkCovidNet model has been proposed for binary and multi-class classification of COVID-19, no-Findings and pneumonia cases.
Togaçar et al. (2020) [255] Automatic COVID-19 diagnosis CXR CNN 458 295 99.27 Features are extracted using deep learning architectures and classified by SVM.
Mahmud et al. (2020) [256] Automatic COVID-19 diagnosis CXR CNN 6161 305 97.4 CovXNet architecture is proposed based on depthwise dilated convolutions.
Mahmoud et al. (2021) [257] Automatic COVID-19 diagnosis CXR CNN 15,496 589 95.82 The CovidXrayNet model has been proposed for three-class classification.
Quan et al. (2021) [258] Classification and segmentation of COVID-19 lesions CXR CNN 9432 781 90.7 The DenseCapsNet has been proposed.
Karakanis and Leontidis (2021) [259] Automatic COVID-19 diagnosis CXR CNN and GAN 435 145 98.7 The GAN model has been used for data augmentation.
Jin et al. (2021) [260] Automatic COVID-19 diagnosis CXR CNN 1743 543 98.64 A hybrid ensemble model, including a pre-trained AlexNet as feature extractor and an SVM classifier as the classifier, has been proposed.
Ahmad et al. (2021) [261] Automatic COVID-19 diagnosis CXR CNN 4000 1000 98.45 Some of the existing CNN architectures with data augmentation have been used for COVID-19 diagnosis.
Zhang et al. (2021) [262] Automatic COVID-19 diagnosis CXR CNN 11,106 5806 An AUC of 0.92 has been achieved for CV19-Net deep neural network architecture. The results show that the proposed method works better in diagnosing COVID-19 than experienced thoracic radiologists.
Wehbe et al. (2021) [263] Automatic COVID-19 diagnosis CXR CNN 14,002 5445 83 The DeepCOVID-XR architecture shows similar performance to experienced thoracic radiologists.
Keidar et al. (2021) [264] Automatic COVID-19 diagnosis CXR CNN 2426 1289 90.3 Some pre-trained deep CNN architectures with data augmentation have been used.
Li et al. (2020) [265] Automatic COVID-19 diagnosis CT CNN 4356 1296 An AUC of 0.96 for detecting COVID-19 has been achieved.
Huang et al. (2020) [266] Evaluation of lung burden changes in patients with COVID-19 CT CNN 126 126 A commercially available deep-learning-based tool has been used.
Zheng et al. (2020) [118] Automatic COVID-19 diagnosis CT CNN 630 90.1 A pre-trained U-Net for lung segmentation and a 3D CNN architecture (DeCoVNet) have been used.
Chen et al. (2020) [267] Automatic COVID-19 diagnosis CT CNN 35,355 20,886 95.24 U-NET++ has been used for retrospective and prospective COVID-19 dataset evaluation.
Hu et al. (2020) [119] Automatic COVID-19 diagnosis CT CNN 450 150 96.2 A weakly-supervised deep learning framework for fast and fully-automated detection and classification of COVID-19 has been presented.
Loey et al. (2020) [116] Automatic COVID-19 diagnosis CT CNN and CGAN 742 345 82.91 Data augmentations along with CGAN improve the performance of classification in AlexNet, VGGNet16, VGGNet19, GoogleNet, and ResNet50 deep transfer models.
Wu et al. (2020) [268] Classification and Segmentation for COVID-19 diagnosis CT CNN 144,167 68,626 A Joint Classification and Segmentation (JCS) system obtains an average sensitivity of 95.0% and a specificity of 93.0% on the classification test set, and 78.3% Dice score on the segmentation test set.
Li et al. (2020) [269] Automatic COVID-19 diagnosis CT CNN 4352 1292 The sensitivity and specificity for detecting COVID-19 are 90% and 96% respectively, with an AUC of 0.96.
Bai et al. (2020) [270] Differentiating COVID-19 and other pneumonia CT CNN 132,583 96 Artificial intelligence improved radiologists' performance in distinguishing COVID-19 from other pneumonia.
Pu et al. (2020) [271] Automatic COVID-19 diagnosis CT CNN 955 498 An AUC of 0.70 has been achieved.
Ni et al. (2020) [272] Automatic COVID-19 diagnosis CT CNN 19,291 3854 94 The deep learning model improves diagnosis efficiency by shortening processing time.
Li et al. (2020) [273] Segmentation of COVID-19 chest CT images CT CNN 558 558 The dice coefficient between the proposed method's segmentation and two experienced radiologists for the COVID-19-infected lung abnormalities is 0.74 and 0.76, respectively.
Ardakani et al. (2020) [274] Automatic COVID-19 diagnosis CT CNN 1020 510 99.63 Different well-known CNN architectures were evaluated for COVID-19 diagnosis. ResNet-101 and Xception show the best performance.
Amyar et al. (2020) [275] Classification and segmentation of COVID-19 lesions CT AE 1369 449 94.67 The dice coefficient of 88% was obtained using multi-task deep learning based model for image segmentation.
Serte and Demirel (2021) [276] Automatic COVID-19 diagnosis CT CNN 7572 2496 98 The proposed method combined the ResNet-50 model and the majority voting with an AUC of 96% as the best result.
Arora et al. (2021) [277] Automatic COVID-19 diagnosis CT CNN 3294 1601 100 Some of the pre-trained deep models have been evaluated for COVID-19 diagnosis using CT images.
Zhao et al. (2021) [278] Segmentation of COVID-19 lesions CT CNN 2317 2317 A dilated dual attention U-Net based on the dual attention strategy and hybrid dilated convolutions has been proposed for COVID-19 lesion segmentation in CT images. A Dice score of 0.72 has been achieved.
Maghdid et al. (2020) [279] Automatic COVID-19 diagnosis CXR and CT CNN CXR: 170
CT: 361
CXR: 85
CT: 203
98 The utilised models can provide accuracy up to 98% via pre-trained AlexNet and 94.1% accuracy by using the modified CNN.
Jia et al. (2021) [280] Automatic COVID-19 diagnosis CXR and CT CNN CXR: 7592
CT: 104,009
CXR: 1770
CT: Not clear
CXR: 99.6
CT: 99.3
The modified MobileNet and ResNet have been proposed.
Chaudhary and Pachori (2021) [281] Automatic COVID-19 diagnosis CXR and CT CNN CXR: 1446
CT: 2481
CXR: 482
CT: 1252
CXR: 100
CT: 97.6
The combination of Fourier-Bessel series expansion-based image decomposition, different CNN architectures and various classifiers have been evaluated.
Ibrahim et al. (2021) [282] Automatic COVID-19 diagnosis CXR and CT CNN and GRU 33,676 4320 98.05 A multi-class classification method including VGG19 and some additional CNN layers shows the best performance.