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. 2021 May 31;16:100462. doi: 10.1016/j.ebr.2021.100462

Table 1.

Supplementary examinations.

Test Date of test Result
MRI 1992 Normal
2003 3 Tesla MRI normal
2007 Slightly atrophy over the right frontoparietal region
2012 More marked atrophy, most prominent in the right frontal lobe. Increased enhancement in different areas in the right hemisphere, some resembling edema
2016 Increased atrophy in the right frontoparietal region
2019-April Considerable loss of brain substance in the right hemisphere and in mesencephalon, pons and diffuse symmetrical atrophy of cerebellum.
2019- June New edema with diffusion restriction in the right cortical parietooccipital region and in the right thalamus, representing ictal/ post ictal activity
2019-Septembre Considerable loss of brain substance in the right hemisphere and in mesencephalon, pons and cerebellum - unchanged from April 2019
Brain pathology 2012 Brain biopsy: reactive gliosis and nerve cell loss in the gray matter of the brain, slight lymphocyte infiltration. Immunostaining for B and T cells did not show any significant changes except for a few CD3 positive T-cells perivascularly. No increase in CD20 positive B-cells.
Cerebrospinal fluid 2000 Slight increase in leucocytes
2012/ 2013/2019 Normal with regards to cell count, protein, glucose ratio. Encephalitis antibodies negative for: anti-NMDA, AMPA1, AMPA 2, Gabareceptor B1, Contactin-associated protein 2, Leucin-rich glioma- inactivated protein 1, anti-CASPR2, anti-DPPX
Blood tests 1992–2020 SR, CRP, white blood count: normal; encephalitis antibodies: Negative
EEG 2002 Epileptiform discharges were present and most prominent in the right frontal region, but also seen in in the temporal region
2019-June Focal status epilepticus, with some clinical seizures starting in the right occipital region
2019-September Slow (theta and delta) activity bilaterally, and additionally more focal slowing over the right frontotemporal region. Sharp waves were also seen in this region, but were less frequent than in July