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. 2021 Jun 22;11:13046. doi: 10.1038/s41598-021-92007-3

Figure 2.

Figure 2

Summary of the metagenomic analysis of the microbiome originating from bacterial cells at baseline. The placebo and the ID-JPL934 groups are comparable in the bacterial composition at the phylum (A) and family levels (B). Microbial diversity is not significantly different between the placebo and the ID-JPL934 groups (C, p > 0.05). In β-diversity index, no significant difference was observed between the two groups (PERMANOVA p > 0.05, Bray–Curtis distance, D). The figure shows the ordination plot of the OTUs at the phylum level (E). Scatter plots of first 2 PC loadings in the canonical analysis of principal coordinates (F,G). Arrows indicate components of the clinical variables. Some of the clinical variables including stool consistency and fiber intake appear to correlate with the ordination. In contrast, age, BMI, and abdominal symptom show limited correlation with the ordination. CHO, carbohydrate; BMI, body mass index.