Table 1.
Baseline characteristics of study subjects.
| ID-JPL934 group | Placebo group | P-value | |
|---|---|---|---|
| (n = 56) | (n = 56) | ||
| Age | 38.9 ± 12.2 | 37.3 ± 1.7 | 0.467 |
| Male, n (%) | 14 (25.0) | 21 (37.5) | 0.259 |
| Smoker, n (%) | 7 (12.5) | 5 (9.1) | 0.795 |
| Drinker, n (%) | 30 (53.6) | 38 (69.1) | 0.178 |
| Body mass index (kg/m2) | 27.9 ± 4.1 | 27.4 ± 4.5 | 0.553 |
| Stool form (BSFS) | 4.14 ± 1.58 | 4.00 ± 1.75 | 0.653 |
| Abnormal bowel movement symptoms | |||
| Stool frequency/day | 1.47 ± 1.04 | 1.52 ± 1.12 | 0.808 |
| Abdominal paina | 2.78 ± 1.64 | 2.96 ± 1.71 | 0.576 |
| Abdominal discomforta | 3.03 ± 1.54 | 3.03 ± 1.75 | 0.955 |
| Constipation scorea | 2.08 ± 1.79 | 2.55 ± 2.35 | 0.243 |
| Diarrhea scorea | 2.78 ± 2.64 | 2.85 ± 3.02 | 0.894 |
| Abdominal bloatinga | 3.30 ± 2.13 | 3.51 ± 2.68 | 0.641 |
| Flatulencea | 3.05 ± 2.11 | 4.00 ± 2.55 | 0.035 |
| Dietary intakes | |||
| Calories (kcal/day) | 1,671.8 ± 448.7 | 1,585.2 ± 388.8 | 0.280 |
| Carbohydrate (g/day) | 231.9 ± 65.9 | 229.0 ± 63.4 | 0.815 |
| Fat (g/day) | 50.2 ± 18.7 | 44.1 ± 14.1 | 0.055 |
| Protein (g/day) | 64.5 ± 20.8 | 60.9 ± 16.4 | 0.826 |
| Dietary fiber (g/day) | 17.4 ± 5.9 | 17.1 ± 6.3 | 0.316 |
| Folate (μg/day) | 334.1 ± 108.8 | 329.3 ± 103.1 | 0.810 |
| Calcium (mg/day) | 377.5 ± 155.7 | 345.3 ± 155.8 | 0.279 |
Data presented as mean ± SD. P-values were calculated by either χ2 test (categorical variables) or Student's t-test (continuous variables).
aVisual analog scale (0–10). BMI, body mass index; BSFS, Bristol Stool Form Scale. Bold style indicates statistical significance.